Programma

Tuesday 27th May

Registration

  • 13:30

    Registration Desk Opening

Opening and Welcome

  • 14:00

    Opening Remarks by the Group Coordinators

    Cristina Angeloni , Nazzareno Capitanio

Main Lecture

  • 14:15 - 15:00

    Dietary polyphenols & health: the good (science), the bad (science) and the ugly (truth)

    Prof. Daniele Del Rio - University of Parma

Bioactive compounds to counteract Inflammation and Oxidative Stress

Chairs: Paola Corsetto, Silvana Hrelia

  • 15:00 - 15:15

    Açaí (Euterpe Oleraceae Mart.) Seeds Regulate NF-κB and Nrf2/ARE Pathways Protecting Lung against Acute and Chronic Inflammation

    Nicla Tranchida – University of Messina
  • 15:15 - 15:30

    Modulation of Cell Growth and Metabolism by Natural and Synthetic Iminosugars in Intestinal Tumor Cell Lines

    Thomas Montebugnoli – University of Bologna
  • 15:30 - 15:45

    TiO₂ Nanoparticles' Stealth Assault: From Oxidative Stress to Barrier Disruption in Dynamic Intestinal Models

    Mattia Santoni – University of Bologna
  • 15:45 - 16:00

    Innovative Food Prototype for One Health: Nanotech-Isolated Bioactive Peptides Targeting Oxidative Stress and Inflammation

    Federica Tonolo – University of Padova
  • 16:00 - 16:15

    Phytochemicals possess selective chemopreventive mechanisms that safeguard human myeloid cells from oxidative toxicity

    Maria Russo – Institute of Food Sciences – CNR
  • 16:15 - 16:30

    The CaMKKβ-AMPK-SIRT1 axis is targeted by vicenin-2 in lipopolysaccharide-exposed THP-1 cells

    Alessandro Maugeri – University of Messina
  • 16:30

    Coffee break

Agri-Food Wastes as Natural Source of Bioactive Compounds

Chairs: Stefania Iammetti and Cecilia Prata

  • 17:00 - 17:15

    Properties of green extracted bioactive compounds from buckwheat husk

    Francesca G. Ghidotti – University of Milan
  • 17:15 - 17:30

    Albana grape pomace: extraction and encapsulation into nanovesicles for enhancing valorization

    Simone Rossello – University of Bologna
  • 17:30 - 17:45

    From Dairy Waste to Functional Ingredients: Characterizing Antioxidant Peptides

    Valeria Scalcon – University of Padova
  • 17:45 - 18:00

    Phenolic extract from Olive Mill Waste Water (OMWW) recovers mitochondrial functionalities following H2O2-induced oxidative stress

    Salvatore Antonio Maria Cubisino – University of Catania
  • 18:00 - 18:15

    Biological effects of Solanum tuberosum L. peel extracts obtained with conventional and green methods

    Chiara Zalambani – University of Bologna

Social Programme

  • 20:00

    Social Dinner

Wednesday 28th May

Microbiota, Gut Health, and Metabolic Regulation

Chairs: Cristiana Caliceti and Gianna Ferretti

  • 9:30 - 9:45

    Targeting bile salt hydrolase activity with bioluminescence: an innovative whole-cell bioassay for gut dysbiosis and gastrointestinal disorders

    Angela Punzo – University of Bologna and INBB, National Institute of Biostructures and Biosystems, Rome (Italy)
  • 9:45 - 10:00

    The crucial role of gut microbiota and phenolic compounds in colon cancer prevention

    Alice Cattivelli – University of Modena and Reggio Emilia
  • 10:00 - 10:15

    The food supplement based on Spermidine and Eugenol is able to protect intestinal cells from inflammation through the activation of autophagy

    Francesca Truzzi – University of Bologna
  • 10:15 - 10:30

    Exploring Gluten-free Diet: Effects on Gut Microbiota and Symptoms in Patients with Gluten-related Disorders and Healthy Subjects

    Anna Costanzini – University of Ferrara
  • 10:30 - 10:45

    Nutrition intervention in disease prevention: modeling gut barrier models to study the phytocompounds bioactivity

    Alessandra Bulbarelli – University of Milano Bicocca
  • 10:45

    Coffee break

Nutraceuticals and neurodegeneration

Chairs: Cristina Angeloni and Paola Coccetti

  • 11:15 - 11:30

    Protective role of verbascoside against misfolding and aggregation of α-synuclein associated with Parkinson’s disease

    Giorgia Spandri – University of Milano-Bicocca
  • 12:30

    Lunch

  • 11:30 - 11:45

    Consumption of Cashew nuts on oxidative stress and neuroinflammation markers in a hyperhomocysteinemic condition

    Alessia Arangia – University of Messina
  • 11:45 - 12:00

    Whatever happened to Oleocanthal and Oleacein? A biological explanation of the reaction with amines in biological fluids

    Davide Laurenti – Sapienza University of Rome
  • 12:00 - 12:15

    Use of olive oil polyphenols to counteract neuroinflammation and neurodegenerative diseases

    Daniel Di Risola – Sapienza University of Rome
  • 12:15 - 12:30

    Elucidating the Molecular Mechanisms of Oleocanthal and Oleocanthalic Acid in Neuroinflammation

    Irene Rinaldi – University of Bologna
  • 12:30 - 14:00

    Lunch

Main Lecture

  • 14:00

    Putting riboflavin derived redox cofactors in their correct places

    Maria Barile - University of Bari "A. Moro"

Membrane Transporters, Extracellular Vesicles and Lipidomics

Chairs: Rosella Scrima and Giancarlo Solaini

  • 14:45 - 15:00

    Impact of 7-ketocholesterol on the function and stability of the LAT1 transporter: possible role in human physiopathology

    Raffaella Scanga – University of Calabria
  • 15:00 - 15:15

    Membrane Lipid Composition of Extracellular Vesicles: A Key Determinant of Their Origin, Trafficking, and Biological Function

    Sandra Buratta – University of Perugia
  • 15:15 - 15:30

    SLC3A2 role in the membrane trafficking of amino acid transporters belonging to the SLC7 family

    Lara Console – University of Calabria
  • 15:30 - 15:45

    Impact of epicatechin on erythrocyte metabolism and evaluation of its protective action on the erythrocyte membrane

    Stefano Putaggio – University of Messina
  • 15:45 - 16:00

    The expression of vegfr2 r1051q alters receptor membrane dynamics and cell metabolism

    Camilla Maggi – University of Brescia
  • 16:00 - 16:30

    Coffee break

Diet, Disease Prevention, and Population Health

Chairs: Tiziana Bacchetti and Antonello Lorenzini

  • 16:30 - 16:45

    Dietary habits of the Italian population across the last 30 years: main features and room for improvement

    Marco Amato – University of Bologna
  • 16:45 - 17:00

    Umbrella review of systematic reviews with meta-analyses on consumption of different food groups and risk of cardiovascular diseases incidence and mortality

    Matteo Perillo - University of Bologna
  • 17:00 - 17:15

    Dietary considerations in autism spectrum disorders: the potential role of Coriolus Versicolor as TLR-4/MYD88/Nf-kb modulator

    Francesca Inferrera – University of Messina
  • 17:15 - 17:30

    Glabranin as a natural modulator of AMPK signaling and lipid metabolism in non-alcoholic fatty liver disease

    Hind Moukham – University of Milano-Bicocca
  • 17:30 - 17:45

    Rhodiola rosea L. extract: A promising approach for metabolic syndrome through mitochondrial respiratory activity modulation and enhanced glucose uptake

    Luca Pincigher – University of Bologna
  • 17:45 - 18:00

    Synergistic Effects of Hyaluronic Acid, Epigallocatechin-3-O-gallate, and Xanthohumol on NF-κB Pathway Modulation in a Rheumatoid Arthritis Model

    Ignazio Restivo – University of Palermo

Thursday 29th May

Allergens, Environmental Contaminants, and Protein Innovation

Chairs: Nazzareno Capitanio and Annamaria Giudetti

  • 9:00 - 9:15

    Hazelnut allergen Cor a 8 is a moonlighting enzyme with lipolytic activity

    Mauro Marengo – University of Turin
  • 9:15 - 9:30

    Microbial transglutaminase as a tool to modify insect proteins

    Loredana Mariniello - University of Naples Federico II
  • 9:30 - 9:45

    Exploring the effects of Bee Pollen in Mesenchymal Stem Cell cultures

    Pasquale Marrazzo – University of Urbino Carlo Bo
  • 9:45 - 10:00

    Impact of heavy metals on the OCTN1 transporter function: Possible Role in Microplastic Threats

    Luana S. Brunetti – University of Calabria
  • 10:00 - 10:15

    Longitudinal intraocular imaging of liver spheroids to uncover novel aspects of liver physiology and pathology

    Noah Moruzzi - Karolinska Institutet

10:15 Speed talk session

Chairs: Ignazio Restivo and Raffaella Scanga

  • 10:15 - 10:20

    Biochemical Properties of Sardinian Legumes: Investigating α-Amylase Inhibition for Nutraceutical Applications and Sardinian Crop Diversity

    Paolo Zucca – University of Cagliari
  • 10:20 - 10:25

    Histone Lipidation in Breast Cancer: the epigenetic role of BRCA1

    Marilena Pontoriero – University of Catanzaro “Magna Græcia”
  • 10:25 - 10:30

    Emerging Neurological Implications of Alkaptonuria: Evidence for HGA-Induced Neuroinflammation in BV-2 Microglia

    Maria Cristina Barbalace – University of Bologna
  • 10:30 - 10:35

    A One Health Approach to Sustainable Nutrition: Developing a Bioactive Peptide-Enriched Food Prototype

    Mary Bortoluzzi – University of Padova
  • 10:35 - 10:40

    Protein Cargo of Extracellular Vesicles Isolated from Donkey Colostrum and Milk

    Elisabetta Chiaradia – University of Perugia
  • 10:40 - 10:45

    The power of nutraceutical compounds: preventing the mitochondrial permeability transition pore opening by targeting F-ATPase

    Cristina Algieri – University of Bologna
  • 11:00 - 11:30

    Coffee break

Mitochondrial Dynamics and Cellular Metabolism

Chairs: Maria Barile and Lara Console

  • 11:30 - 11:45

    Clockwork Cells: circadian control of mitochondrial functions

    Michela Rosiello – University of Foggia
  • 11:45 - 12:00

    Circadian Mitochondrial Dysfunction in Cellular Models of Early-Onset Parkinson’s Disease with PARK2 Mutations

    Mirko Tamma – University of Foggia
  • 12:00 - 12:15

    Anti-cancer VA molecules trigger profound alterations in VDAC1 electrophysiology

    Stefano Conti Nibali – University of Catania
  • 12:15 - 12:30

    Honokiol blocks tumor development and metastasis through mitochondrion-targeted effects

    Valentina Giorgio – University of Bologna
  • 12:30 - 12:45

    Bioenergetics of cancer cells: the pro-oncogenic protein IF1 and metabolic reprogramming

    Valentina Del Dotto – University of Bologna

Prizes

  • 12:45

    Awards and Recognitions Ceremony

Closing remarks

  • 13:15

    Closing Remarks and Farewell to Participants

    Cristina Angeloni and Nazzareno Capitanio