Programma
Tuesday 27th May
Registration
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13:30
Registration Desk Opening
Opening and Welcome
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14:00
Opening Remarks by the Group Coordinators
Cristina Angeloni , Nazzareno Capitanio
Main Lecture
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14:15 - 15:00
Dietary polyphenols & health: the good (science), the bad (science) and the ugly (truth)
Prof. Daniele Del Rio - University of Parma
Bioactive compounds to counteract Inflammation and Oxidative Stress
Chairs: Paola Corsetto, Silvana Hrelia
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15:00 - 15:15
Açaí (Euterpe Oleraceae Mart.) Seeds Regulate NF-κB and Nrf2/ARE Pathways Protecting Lung against Acute and Chronic Inflammation
Nicla Tranchida – University of Messina -
15:15 - 15:30
Modulation of Cell Growth and Metabolism by Natural and Synthetic Iminosugars in Intestinal Tumor Cell Lines
Thomas Montebugnoli – University of Bologna -
15:30 - 15:45
TiO₂ Nanoparticles' Stealth Assault: From Oxidative Stress to Barrier Disruption in Dynamic Intestinal Models
Mattia Santoni – University of Bologna -
15:45 - 16:00
Innovative Food Prototype for One Health: Nanotech-Isolated Bioactive Peptides Targeting Oxidative Stress and Inflammation
Federica Tonolo – University of Padova -
16:00 - 16:15
Phytochemicals possess selective chemopreventive mechanisms that safeguard human myeloid cells from oxidative toxicity
Maria Russo – Institute of Food Sciences – CNR -
16:15 - 16:30
The CaMKKβ-AMPK-SIRT1 axis is targeted by vicenin-2 in lipopolysaccharide-exposed THP-1 cells
Alessandro Maugeri – University of Messina -
16:30
Coffee break
Agri-Food Wastes as Natural Source of Bioactive Compounds
Chairs: Stefania Iammetti and Cecilia Prata
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17:00 - 17:15
Properties of green extracted bioactive compounds from buckwheat husk
Francesca G. Ghidotti – University of Milan -
17:15 - 17:30
Albana grape pomace: extraction and encapsulation into nanovesicles for enhancing valorization
Simone Rossello – University of Bologna -
17:30 - 17:45
From Dairy Waste to Functional Ingredients: Characterizing Antioxidant Peptides
Valeria Scalcon – University of Padova -
17:45 - 18:00
Phenolic extract from Olive Mill Waste Water (OMWW) recovers mitochondrial functionalities following H2O2-induced oxidative stress
Salvatore Antonio Maria Cubisino – University of Catania -
18:00 - 18:15
Biological effects of Solanum tuberosum L. peel extracts obtained with conventional and green methods
Chiara Zalambani – University of Bologna
Social Programme
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20:00
Social Dinner
Wednesday 28th May
Microbiota, Gut Health, and Metabolic Regulation
Chairs: Cristiana Caliceti and Gianna Ferretti
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9:30 - 9:45
Targeting bile salt hydrolase activity with bioluminescence: an innovative whole-cell bioassay for gut dysbiosis and gastrointestinal disorders
Angela Punzo – University of Bologna and INBB, National Institute of Biostructures and Biosystems, Rome (Italy) -
9:45 - 10:00
The crucial role of gut microbiota and phenolic compounds in colon cancer prevention
Alice Cattivelli – University of Modena and Reggio Emilia -
10:00 - 10:15
The food supplement based on Spermidine and Eugenol is able to protect intestinal cells from inflammation through the activation of autophagy
Francesca Truzzi – University of Bologna -
10:15 - 10:30
Exploring Gluten-free Diet: Effects on Gut Microbiota and Symptoms in Patients with Gluten-related Disorders and Healthy Subjects
Anna Costanzini – University of Ferrara -
10:30 - 10:45
Nutrition intervention in disease prevention: modeling gut barrier models to study the phytocompounds bioactivity
Alessandra Bulbarelli – University of Milano Bicocca -
10:45
Coffee break
Nutraceuticals and neurodegeneration
Chairs: Cristina Angeloni and Paola Coccetti
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11:15 - 11:30
Protective role of verbascoside against misfolding and aggregation of α-synuclein associated with Parkinson’s disease
Giorgia Spandri – University of Milano-Bicocca -
12:30
Lunch
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11:30 - 11:45
Consumption of Cashew nuts on oxidative stress and neuroinflammation markers in a hyperhomocysteinemic condition
Alessia Arangia – University of Messina -
11:45 - 12:00
Whatever happened to Oleocanthal and Oleacein? A biological explanation of the reaction with amines in biological fluids
Davide Laurenti – Sapienza University of Rome -
12:00 - 12:15
Use of olive oil polyphenols to counteract neuroinflammation and neurodegenerative diseases
Daniel Di Risola – Sapienza University of Rome -
12:15 - 12:30
Elucidating the Molecular Mechanisms of Oleocanthal and Oleocanthalic Acid in Neuroinflammation
Irene Rinaldi – University of Bologna -
12:30 - 14:00
Lunch
Main Lecture
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14:00
Putting riboflavin derived redox cofactors in their correct places
Maria Barile - University of Bari "A. Moro"
Membrane Transporters, Extracellular Vesicles and Lipidomics
Chairs: Rosella Scrima and Giancarlo Solaini
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14:45 - 15:00
Impact of 7-ketocholesterol on the function and stability of the LAT1 transporter: possible role in human physiopathology
Raffaella Scanga – University of Calabria -
15:00 - 15:15
Membrane Lipid Composition of Extracellular Vesicles: A Key Determinant of Their Origin, Trafficking, and Biological Function
Sandra Buratta – University of Perugia -
15:15 - 15:30
SLC3A2 role in the membrane trafficking of amino acid transporters belonging to the SLC7 family
Lara Console – University of Calabria -
15:30 - 15:45
Impact of epicatechin on erythrocyte metabolism and evaluation of its protective action on the erythrocyte membrane
Stefano Putaggio – University of Messina -
15:45 - 16:00
The expression of vegfr2 r1051q alters receptor membrane dynamics and cell metabolism
Camilla Maggi – University of Brescia -
16:00 - 16:30
Coffee break
Diet, Disease Prevention, and Population Health
Chairs: Tiziana Bacchetti and Antonello Lorenzini
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16:30 - 16:45
Dietary habits of the Italian population across the last 30 years: main features and room for improvement
Marco Amato – University of Bologna -
16:45 - 17:00
Umbrella review of systematic reviews with meta-analyses on consumption of different food groups and risk of cardiovascular diseases incidence and mortality
Matteo Perillo - University of Bologna -
17:00 - 17:15
Dietary considerations in autism spectrum disorders: the potential role of Coriolus Versicolor as TLR-4/MYD88/Nf-kb modulator
Francesca Inferrera – University of Messina -
17:15 - 17:30
Glabranin as a natural modulator of AMPK signaling and lipid metabolism in non-alcoholic fatty liver disease
Hind Moukham – University of Milano-Bicocca -
17:30 - 17:45
Rhodiola rosea L. extract: A promising approach for metabolic syndrome through mitochondrial respiratory activity modulation and enhanced glucose uptake
Luca Pincigher – University of Bologna -
17:45 - 18:00
Synergistic Effects of Hyaluronic Acid, Epigallocatechin-3-O-gallate, and Xanthohumol on NF-κB Pathway Modulation in a Rheumatoid Arthritis Model
Ignazio Restivo – University of Palermo
Thursday 29th May
Allergens, Environmental Contaminants, and Protein Innovation
Chairs: Nazzareno Capitanio and Annamaria Giudetti
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9:00 - 9:15
Hazelnut allergen Cor a 8 is a moonlighting enzyme with lipolytic activity
Mauro Marengo – University of Turin -
9:15 - 9:30
Microbial transglutaminase as a tool to modify insect proteins
Loredana Mariniello - University of Naples Federico II -
9:30 - 9:45
Exploring the effects of Bee Pollen in Mesenchymal Stem Cell cultures
Pasquale Marrazzo – University of Urbino Carlo Bo -
9:45 - 10:00
Impact of heavy metals on the OCTN1 transporter function: Possible Role in Microplastic Threats
Luana S. Brunetti – University of Calabria -
10:00 - 10:15
Longitudinal intraocular imaging of liver spheroids to uncover novel aspects of liver physiology and pathology
Noah Moruzzi - Karolinska Institutet
10:15 Speed talk session
Chairs: Ignazio Restivo and Raffaella Scanga
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10:15 - 10:20
Biochemical Properties of Sardinian Legumes: Investigating α-Amylase Inhibition for Nutraceutical Applications and Sardinian Crop Diversity
Paolo Zucca – University of Cagliari -
10:20 - 10:25
Histone Lipidation in Breast Cancer: the epigenetic role of BRCA1
Marilena Pontoriero – University of Catanzaro “Magna Græcia” -
10:25 - 10:30
Emerging Neurological Implications of Alkaptonuria: Evidence for HGA-Induced Neuroinflammation in BV-2 Microglia
Maria Cristina Barbalace – University of Bologna -
10:30 - 10:35
A One Health Approach to Sustainable Nutrition: Developing a Bioactive Peptide-Enriched Food Prototype
Mary Bortoluzzi – University of Padova -
10:35 - 10:40
Protein Cargo of Extracellular Vesicles Isolated from Donkey Colostrum and Milk
Elisabetta Chiaradia – University of Perugia -
10:40 - 10:45
The power of nutraceutical compounds: preventing the mitochondrial permeability transition pore opening by targeting F-ATPase
Cristina Algieri – University of Bologna -
11:00 - 11:30
Coffee break
Mitochondrial Dynamics and Cellular Metabolism
Chairs: Maria Barile and Lara Console
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11:30 - 11:45
Clockwork Cells: circadian control of mitochondrial functions
Michela Rosiello – University of Foggia -
11:45 - 12:00
Circadian Mitochondrial Dysfunction in Cellular Models of Early-Onset Parkinson’s Disease with PARK2 Mutations
Mirko Tamma – University of Foggia -
12:00 - 12:15
Anti-cancer VA molecules trigger profound alterations in VDAC1 electrophysiology
Stefano Conti Nibali – University of Catania -
12:15 - 12:30
Honokiol blocks tumor development and metastasis through mitochondrion-targeted effects
Valentina Giorgio – University of Bologna -
12:30 - 12:45
Bioenergetics of cancer cells: the pro-oncogenic protein IF1 and metabolic reprogramming
Valentina Del Dotto – University of Bologna
Prizes
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12:45
Awards and Recognitions Ceremony
Closing remarks
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13:15
Closing Remarks and Farewell to Participants
Cristina Angeloni and Nazzareno Capitanio